Semaglutide
GLP-1 receptor agonist. Reference standard.
Also known as: SM · SM5 · SM10 · SM15 · SM20 · SM30 · Sema · GLP-1 agonist
CAS 910463-68-2 · C187H291N45O59
Lead time
Ships in 3–5 days
Purity
99.4%
CAS Number
910463-68-2
Molecular Weight
4113.6
Formula
C187H291N45O59
Form
Lyophilized powder
Packaging
5mg vial · 10 vials/box
Storage
-20°C, lyophilized
Solubility
Water
Chemical structure

2D structure · Source: PubChem (NIH)
Research applications
Semaglutide is a long-acting GLP-1 receptor agonist with 94% sequence homology to native human GLP-1, stabilized by an Aib substitution at position 8 and a C18 fatty-acid chain enabling strong albumin binding. It is widely used as a reference standard in GLP-1 receptor binding assays, insulinotropic research, appetite and food-intake studies, and formulation-stability testing. This lyophilized research peptide is sequence-verified and supplied with HPLC purity documentation.
Referenced literature
- [1]Wilding J.P.H., et al. "Once-Weekly Semaglutide in Adults with Overweight or Obesity." New England Journal of Medicine, 2021 (STEP 1).
- [2]Marso S.P., et al. "Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes." New England Journal of Medicine, 2016 (SUSTAIN-6).
Selected peer-reviewed literature for research context — not medical advice.
Quality Documentation
How we verifyRaw material screening
Off-spec lots never enter synthesis
In-process monitoring
Intermediates characterized at checkpoints
HPLC-MS verification
Identity, purity & quantitation per batch
A batch-specific COA ships with every order — see the format before you buy.
Request sample COAFrequently asked questions
What is Semaglutide?
Semaglutide is a long-acting GLP-1 receptor agonist with 94% sequence homology to native human GLP-1, stabilized by an Aib substitution at position 8 and a C18 fatty-acid chain enabling strong albumin binding. It is widely used as a reference standard in GLP-1 receptor binding assays, insulinotropic research, appetite and food-intake studies, and formulation-stability testing. This lyophilized research peptide is sequence-verified and supplied with HPLC purity documentation.
What purity is Semaglutide?
99.4% purity, HPLC-MS verified per batch.
What is the CAS number of Semaglutide?
CAS 910463-68-2 · Molecular formula C187H291N45O59 · Molecular weight 4113.6.
How long does Semaglutide take to ship?
Ships in 3–5 days after order confirmation.
How should Semaglutide be stored?
-20°C, lyophilized. Solubility: Water.
Is Semaglutide for human use?
No. Semaglutide is a research compound for laboratory research use only — not for human or veterinary use.
For pricing and availability of Semaglutide, contact our research team.
For laboratory research use only.
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