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GLP-1 Agonists

Semaglutide

GLP-1 receptor agonist. Reference standard.

Also known as: SM · SM5 · SM10 · SM15 · SM20 · SM30 · Sema · GLP-1 agonist

CAS 910463-68-2 · C187H291N45O59

Lead time

Ships in 3–5 days

Purity

99.4%

CAS Number

910463-68-2

Molecular Weight

4113.6

Formula

C187H291N45O59

Form

Lyophilized powder

Packaging

5mg vial · 10 vials/box

Storage

-20°C, lyophilized

Solubility

Water

Chemical structure

Semaglutide 2D chemical structure

2D structure · Source: PubChem (NIH)

Research applications

Semaglutide is a long-acting GLP-1 receptor agonist with 94% sequence homology to native human GLP-1, stabilized by an Aib substitution at position 8 and a C18 fatty-acid chain enabling strong albumin binding. It is widely used as a reference standard in GLP-1 receptor binding assays, insulinotropic research, appetite and food-intake studies, and formulation-stability testing. This lyophilized research peptide is sequence-verified and supplied with HPLC purity documentation.

Referenced literature

  1. [1]Wilding J.P.H., et al. "Once-Weekly Semaglutide in Adults with Overweight or Obesity." New England Journal of Medicine, 2021 (STEP 1).
  2. [2]Marso S.P., et al. "Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes." New England Journal of Medicine, 2016 (SUSTAIN-6).

Selected peer-reviewed literature for research context — not medical advice.

Quality Documentation

How we verify
1

Raw material screening

Off-spec lots never enter synthesis

2

In-process monitoring

Intermediates characterized at checkpoints

3

HPLC-MS verification

Identity, purity & quantitation per batch

A batch-specific COA ships with every order — see the format before you buy.

Request sample COA

Frequently asked questions

What is Semaglutide?

Semaglutide is a long-acting GLP-1 receptor agonist with 94% sequence homology to native human GLP-1, stabilized by an Aib substitution at position 8 and a C18 fatty-acid chain enabling strong albumin binding. It is widely used as a reference standard in GLP-1 receptor binding assays, insulinotropic research, appetite and food-intake studies, and formulation-stability testing. This lyophilized research peptide is sequence-verified and supplied with HPLC purity documentation.

What purity is Semaglutide?

99.4% purity, HPLC-MS verified per batch.

What is the CAS number of Semaglutide?

CAS 910463-68-2 · Molecular formula C187H291N45O59 · Molecular weight 4113.6.

How long does Semaglutide take to ship?

Ships in 3–5 days after order confirmation.

How should Semaglutide be stored?

-20°C, lyophilized. Solubility: Water.

Is Semaglutide for human use?

No. Semaglutide is a research compound for laboratory research use only — not for human or veterinary use.

For pricing and availability of Semaglutide, contact our research team.

For laboratory research use only.