GuideSeptember 10, 2026 · 1 min read

CJC-1295 + Ipamorelin: The Classic GH-Axis Pair, in Vial Math

Research compounds for laboratory use only · not medical advice

Why a GHRH analog and a selective secretagogue are stacked, what each contributes at the receptor, and how the two vials' reconstitution math actually works day to day.

The most-referenced peptide stack in GH-axis research is really two molecules doing two jobs — and two vial calculations, not one.

What each half contributes

CJC-1295 (no DAC) is a growth-hormone-releasing-hormone analog — the full 1-29 sequence without the drug affinity complex, studied for its short-acting pulse on the GHRH receptor. Ipamorelin is the selective ghrelin-mimetic pentapeptide on GHS-R1a, known in comparative secretagogue work for a cleaner cortisol/prolactin side profile than the older GHRPs (context in the GHRP-6 guide and the ipamorelin vs HGH comparison).

One raises the release instruction; the other tunes the pituitary’s readiness to obey. That complementarity — not redundancy — is why protocols measure them together.

The daily math, done properly

Each vial gets its own bacteriostatic-water dilution and its own calculator run:

Component	Vial	At 2 mL BAC	A 10-unit draw carries
CJC-1295 (no DAC)	2 mg	1.0 mg/mL	100 µg
Ipamorelin	5 mg	2.5 mg/mL	250 µg

Use the reconstitution calculator per vial, the U-100 converter for the syringe column. Both peptides ship lyophilized, stored −20 °C cold after reconstitution; handling steps are identical to the single-peptide protocol.

When a fixed blend is acceptable

Wholesale code sheets carry the pair pre-mixed (codes “CJIPA”-style) for convenience vials; the same 1:1-ratio tradeoff discussed in the BPC+TB blend guide applies — locked ratios simplify handling, sacrifice dosing independence.

For laboratory research use only. Not medical advice.

FAQ

Frequently asked questions

Why stack CJC-1295 with Ipamorelin at all?

Two different receptors on one axis: CJC-1295 (no DAC) is a GHRH-receptor analog that raises the release signal; Ipamorelin is a GHS-R1a agonist that primes the pituitary. Studied together because the secretory output depends on both inputs — the pairing has been the default GH-axis stack in research protocols since the mid-2000s.

One vial or two?

In our catalog, two separate vials (2 mg CJC, 5 mg Ipa). Reconstitute each on its own schedule and draw each dose separately; blended 'combo' vials exist in wholesale code sheets but fix the mass ratio, which this stack usually does not want.

Does the DAC version change the math?

Yes, pharmacokinetically: the original CJC-1295 with DAC carries albumin-binding extensions and a much longer apparent half-life — the no-DAC (Mod GRF 1-29) form in our catalog is the short-acting one matched to pulsed dosing.

What do the two reconstitution calculations look like?

Same form, different numbers: vial mass ÷ BAC water volume gives each concentration independently. At 2 mg in 2 mL, CJC reads 1 mg/mL; at 5 mg in 2 mL, Ipa reads 2.5 mg/mL — same 0.1 mL draw carries 100 µg vs 250 µg. The calculator runs both.

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