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Peptides

MK-677 (Ibutamoren)

Orally active ghrelin-mimetic GH secretagogue (spiro-piperidine, non-peptide).

Also known as: MK677 · MK-677 · Ibutamoren · Ibutamoren mesylate · MK-0677

CAS 159752-10-0 · C28H40N4O8S2

Lead time

Ships in 3–5 days

Purity

99.0%

CAS Number

159752-10-0

Molecular Weight

624.8

Formula

C28H40N4O8S2

Form

Lyophilized powder

Packaging

10mg vial · 10 vials/box

Storage

Room temperature, dry

Solubility

DMSO, ethanol, water (mesylate)

Chemical structure

MK-677 (Ibutamoren) 2D chemical structure

2D structure · Source: PubChem (NIH)

Research applications

MK-677 (ibutamoren mesylate) is an orally active, non-peptide growth-hormone secretagogue that mimics ghrelin at GHS-R1a, raising pulsatile GH and sustained IGF-1. The 12-month randomized trial in healthy older adults (Ann. Intern. Med. 2008) increased fat-free mass without functional gain; the 25 mg hip-fracture program (Adunsky et al., 2011) supplied the key tolerability and glycemic-signal data. It is a reference compound in GH-axis and ghrelin-receptor research.

Quality Documentation

How we verify
1

Raw material screening

Off-spec lots never enter synthesis

2

In-process monitoring

Intermediates characterized at checkpoints

3

HPLC-MS verification

Identity, purity & quantitation per batch

A batch-specific COA ships with every order — see the format before you buy.

Request sample COA

Frequently asked questions

What is MK-677 (Ibutamoren)?

MK-677 (ibutamoren mesylate) is an orally active, non-peptide growth-hormone secretagogue that mimics ghrelin at GHS-R1a, raising pulsatile GH and sustained IGF-1. The 12-month randomized trial in healthy older adults (Ann. Intern. Med. 2008) increased fat-free mass without functional gain; the 25 mg hip-fracture program (Adunsky et al., 2011) supplied the key tolerability and glycemic-signal data. It is a reference compound in GH-axis and ghrelin-receptor research.

What purity is MK-677 (Ibutamoren)?

99.0% purity, HPLC-MS verified per batch.

What is the CAS number of MK-677 (Ibutamoren)?

CAS 159752-10-0 · Molecular formula C28H40N4O8S2 · Molecular weight 624.8.

How long does MK-677 (Ibutamoren) take to ship?

Ships in 3–5 days after order confirmation.

How should MK-677 (Ibutamoren) be stored?

Room temperature, dry. Solubility: DMSO, ethanol, water (mesylate).

Is MK-677 (Ibutamoren) for human use?

No. MK-677 (Ibutamoren) is a research compound for laboratory research use only — not for human or veterinary use.

For pricing and availability of MK-677 (Ibutamoren), contact our research team.

For laboratory research use only.