MK-677 (Ibutamoren)
Orally active ghrelin-mimetic GH secretagogue (spiro-piperidine, non-peptide).
Also known as: MK677 · MK-677 · Ibutamoren · Ibutamoren mesylate · MK-0677
CAS 159752-10-0 · C28H40N4O8S2
Lead time
Ships in 3–5 days
Purity
99.0%
CAS Number
159752-10-0
Molecular Weight
624.8
Formula
C28H40N4O8S2
Form
Lyophilized powder
Packaging
10mg vial · 10 vials/box
Storage
Room temperature, dry
Solubility
DMSO, ethanol, water (mesylate)
Chemical structure

2D structure · Source: PubChem (NIH)
Research applications
MK-677 (ibutamoren mesylate) is an orally active, non-peptide growth-hormone secretagogue that mimics ghrelin at GHS-R1a, raising pulsatile GH and sustained IGF-1. The 12-month randomized trial in healthy older adults (Ann. Intern. Med. 2008) increased fat-free mass without functional gain; the 25 mg hip-fracture program (Adunsky et al., 2011) supplied the key tolerability and glycemic-signal data. It is a reference compound in GH-axis and ghrelin-receptor research.
Quality Documentation
How we verifyRaw material screening
Off-spec lots never enter synthesis
In-process monitoring
Intermediates characterized at checkpoints
HPLC-MS verification
Identity, purity & quantitation per batch
A batch-specific COA ships with every order — see the format before you buy.
Request sample COAFrequently asked questions
What is MK-677 (Ibutamoren)?
MK-677 (ibutamoren mesylate) is an orally active, non-peptide growth-hormone secretagogue that mimics ghrelin at GHS-R1a, raising pulsatile GH and sustained IGF-1. The 12-month randomized trial in healthy older adults (Ann. Intern. Med. 2008) increased fat-free mass without functional gain; the 25 mg hip-fracture program (Adunsky et al., 2011) supplied the key tolerability and glycemic-signal data. It is a reference compound in GH-axis and ghrelin-receptor research.
What purity is MK-677 (Ibutamoren)?
99.0% purity, HPLC-MS verified per batch.
What is the CAS number of MK-677 (Ibutamoren)?
CAS 159752-10-0 · Molecular formula C28H40N4O8S2 · Molecular weight 624.8.
How long does MK-677 (Ibutamoren) take to ship?
Ships in 3–5 days after order confirmation.
How should MK-677 (Ibutamoren) be stored?
Room temperature, dry. Solubility: DMSO, ethanol, water (mesylate).
Is MK-677 (Ibutamoren) for human use?
No. MK-677 (Ibutamoren) is a research compound for laboratory research use only — not for human or veterinary use.
For pricing and availability of MK-677 (Ibutamoren), contact our research team.
For laboratory research use only.
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